Where is the site of action for diuretics in the nephron?

Diuretics are a class of medications commonly used to treat conditions such as hypertension and heart failure by increasing urine production. The site of action for diuretics in the nephron is primarily in the distal convoluted tubule and collecting duct. Diuretics work by inhibiting sodium reabsorption in these segments of the nephron, leading to increased excretion of sodium and water, and ultimately reducing fluid retention in the body. By targeting specific parts of the nephron, diuretics help to regulate fluid balance and decrease blood pressure.
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