What are the potential adverse effects of TRP channel inhibitors?

TRP (transient receptor potential) channels are a group of ion channels that play a vital role in various sensory and physiological processes. TRP channel inhibitors are chemicals that can block the activity of these channels and are being investigated as a potential therapeutic target for numerous health conditions. However, these inhibitors may also produce some adverse effects. For instance, inhibiting TRP channels in the vanilloid subgroup could reduce pain sensation, but also cause a reduction in body temperature. Similarly, inhibition of TRP channels in the melastatin subgroup could result in reduced cellular proliferation, but also affect cancer cell apoptosis. Hence, more research is needed to understand the full range of adverse effects that TRP channel inhibitors may cause.

This mind map was published on 22 June 2023 and has been viewed 53 times.