What are the limitations of current ophthalmic delivery systems?

Current ophthalmic delivery systems, such as eye drops and ointments, have several limitations that can hinder their effectiveness. One of the main limitations is poor patient compliance, as repeated dosing throughout the day can be challenging for patients to remember and adhere to. Additionally, these delivery systems can also result in low bioavailability of the active ingredients due to rapid tear turnover and drainage from the eye. Furthermore, the ocular barriers, such as the tear film and corneal epithelium, can limit the penetration of drugs into the eye, reducing their therapeutic efficacy. These limitations highlight the need for novel and improved ophthalmic delivery systems that can overcome these challenges and provide more effective treatment options for ocular diseases.

This mind map was published on 24 February 2025 and has been viewed 30 times.